Helicobacter pylori lectins - identification, characterization, and purification for clinical applications
Professor Lam, Shiu Kum (Principal investigator)
Dr Ching Chi Kong (Co-Investigator)
Dr Zhu (Co-Investigator)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
To improve our understandings of the H.pylori surface lectins and to develop a typing system for H.pylori by using these lectins as markers; to develop an animal model to test if H.pyori lectins could be exploited as vaccine antigens to prevent gastric H.pylori colonization; to test if specific oligosaccharides can displace H.pylori from gastric epithelial surface so that naturally occuring compounds bearing these oligosaccharide epitopes can be used as therapeutic agents to eliminate gastric H.pylori colonization.