Application of recombinant DNA technology in genetic diseases
Grant Data
Project Title
Application of recombinant DNA technology in genetic diseases
Principal Investigator
Emeritus Professor Sir Todd, David
(Principal Investigator)
Start Date
1986-02-05
Amount
1795000
Conference Title
Application of recombinant DNA technology in genetic diseases
Presentation Title
Keywords
null
Discipline
N/A
HKU Project Code
N/A
Grant Type
Croucher Foundation - Research Grants
Funding Year
1986
Status
Completed
Objectives
To simplify the technique for quantitation of globin genes; to identify the specific a gene mutants responsible for [beta] thalassemia in Chinese by direct synthetic oligonucleotide probe analysis; to clone and sequence two abnormal [alpha] globin genes responsible for sever nondeleton [alpha] thalassemia and four new [beta] thalassemia mutants in the Chinese; to determine the restriction fragment length polymorphsim associated with haemophilia and Christmas Disease in Chinese.