Molecular cloning and expression of a cDNA encoding the stanniocalcin receptor


Grant Data
Project Title
Molecular cloning and expression of a cDNA encoding the stanniocalcin receptor
Principal Investigator
Professor Chan, Daniel Kwong On   (Principal investigator)
Co-Investigator(s)
Dr Wong   (Co-Investigator)
Duration
28
Start Date
1998-09-01
Completion Date
2000-12-31
Amount
705000
Conference Title
Presentation Title
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
HKU 7206/98M
Grant Type
General Research Fund (GRF)
Funding Year
1998/1999
Status
Completed
Objectives
To definitively define the sites of action of Stanniocalcin (STC) hormone, which has been assumed for a century to be unique to fish but has recently been identified in mammalian tissue as well. The main action of this hormone is on calcium and inorganic phosphate metabolism. Its site of action has been found to include the chloride cell of the gill epithelium, the kidney tubules, and possibly the bone.