Cellular signals controlling transferrin receptor expression and recycling


Grant Data
Project Title
Cellular signals controlling transferrin receptor expression and recycling
Principal Investigator
Professor Loh, Tatt Tuck   (Principal investigator)
Duration
24
Start Date
1992-07-01
Completion Date
1994-06-30
Amount
28600
Conference Title
Presentation Title
Grant Type
Lee Wing Tat Fund
Funding Year
1992/1993
Status
Completed
Objectives
Transferrin receptor expression and recycling are subject to precise control but the mechnanism has not been fully understood. Since the transferrin receptor expression and recycling are closely linked to cell proliferation and differentiation, we are interested in investigating how various cellular signals particularly those involved in cell proliferation and differentiation, regulate the transferrin receptor expression and display at gene transcription and translation levels as well as by redistribution of surface transferrrin receptor and internal pool.