Hypercarbia and circulatory overload in treated and untreated SHR rats under halothane anaesthesia


Grant Data
Project Title
Hypercarbia and circulatory overload in treated and untreated SHR rats under halothane anaesthesia
Principal Investigator
Dr Jones, Robert Douglas Morrison   (Principal investigator)
Start Date
1989-05-26
Amount
26990
Conference Title
Presentation Title
Grant Type
Wing Lung Bank Medical Research Fund
Funding Year
1989/1990
Status
Completed
Objectives
To ascertain the ability of the spontaneously hypertensive rat to compensate for hypercarbia or fluid overload, and to determine whether treatment with anti-hypertensive medication improves or degrades that compensation. This animal is widely regarded as a relevant model for the investigation of responses to pathophysiological challenges which cannot be ethically studied in humans.