Role of Chinese medicinal compounds in the regulation of stress-activated protein kinase in ischaemia/reperfusion
Dr Siow, Yaw Loong (Principal investigator)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
To investigate the biochemical and molecular mechanisms for the therapeutic use of tetramethylpyrazine (TMP), sodium tanshinone IIA sulphonate (STS) and ginkgo biloba in myocardial ischaemia/reperfusion. Specifically, I plan to determine whether these CChinese medicinal compounds have inhibitory effects against apoptosis mediated by the stress-activated protein (SAP) kinase pathway.