Role of Chinese medicinal compounds in the regulation of stress-activated protein kinase in ischaemia/reperfusion
Grant Data
Project Title
Role of Chinese medicinal compounds in the regulation of stress-activated protein kinase in ischaemia/reperfusion
Principal Investigator
Dr Siow, Yaw Loong
(Principal Investigator)
Duration
35
Start Date
1998-09-01
Amount
735000
Conference Title
Role of Chinese medicinal compounds in the regulation of stress-activated protein kinase in ischaemia/reperfusion
Presentation Title
Keywords
null
Discipline
N/A
HKU Project Code
HKU 7297/98M
Grant Type
General Research Fund (GRF)
Funding Year
1998
Status
Completed
Objectives
To investigate the biochemical and molecular mechanisms for the therapeutic use of tetramethylpyrazine (TMP), sodium tanshinone IIA sulphonate (STS) and ginkgo biloba in myocardial ischaemia/reperfusion. Specifically, I plan to determine whether these CChinese medicinal compounds have inhibitory effects against apoptosis mediated by the stress-activated protein (SAP) kinase pathway.