Gradient diffusion-attenuated NMR spectroscopy for the analysis of multi-component mixtures


Grant Data
Project Title
Gradient diffusion-attenuated NMR spectroscopy for the analysis of multi-component mixtures
Principal Investigator
Dr Brown, Geoffrey Duncan   (Principal investigator)
Duration
24
Start Date
1994-12-01
Completion Date
1996-11-30
Amount
0
Conference Title
Presentation Title
Grant Type
Other Funding Scheme
Funding Year
1994/1995
Status
Completed
Objectives
Spectroscopic analysis of multi-component mixtures has always required a physical separation of the components by some chromatographic technique prior to the acquisition of a characteristic spectrum from each component. In recent years there has been a poliferation of "hyphenated" techniques based on this very principle. The modern capability to generate magnetic-field gradients in NMR Spectroscopy opens up the possibility of differentiating compounds by their diffusion characteristics. The project aims to investigate whether this molecular property can be applied to resolve different components when present simultaneously in the same mixture. If successful, NMR analysis of complex mixtures would then be as simple a matter as NMR analysis of ind ividual compounds, and the need for prior chromatography will have been removed, resulting in greater simplicity and wider applicability of NMR in the analysis of multi-component mixtures.