Plastic response of cancer cells: characterization, modeling and clinical implications
Grant Data
Project Title
Plastic response of cancer cells: characterization, modeling and clinical implications
Principal Investigator
Dr Lin, Yuan
(Principal Investigator (PI))
Co-Investigator(s)
Professor Gao Huajian
(Co-Investigator)
Dr Cho Chi Shing, William
(Co-Investigator)
Duration
36
Start Date
2020-09-01
Amount
614675
Conference Title
Plastic response of cancer cells: characterization, modeling and clinical implications
Presentation Title
Keywords
Cell Mechanics, Cytoskeleton Mechanics, Plasticity
Discipline
Mechanics and Dynamics
Panel
Engineering (E)
HKU Project Code
17210520
Grant Type
General Research Fund (GRF)
Funding Year
2020
Status
On-going
Objectives
1) To develop a microfluidic system for characterizing the plastic response of cells. 2) To systematically measure the plasticity characteristics of different cancer cell lines as well as circulating tumor cells (CTCs) from lung cancer patients. 3) To model the cytoskeleton damage-induced plastic deformation of cells.