PDZD2 and primary open-angle glaucoma: characterization of Pdzd2-deficient mice and human PDZD2 SNPs
Grant Data
Project Title
PDZD2 and primary open-angle glaucoma: characterization of Pdzd2-deficient mice and human PDZD2 SNPs
Principal Investigator
Dr Yao, Kwok Ming
(Principal Investigator (PI))
Co-Investigator(s)
Dr Lo Amy Cheuk Yin
(Co-Investigator)
Duration
36
Start Date
2019-05-01
Amount
1499628
Conference Title
PDZD2 and primary open-angle glaucoma: characterization of Pdzd2-deficient mice and human PDZD2 SNPs
Presentation Title
Keywords
characterization, glaucoma, open-angle, PDZD2, PDZD2 SNPs, Pdzd2-deficient
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
06172876
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2018
Status
Completed
Objectives
Glaucoma, a major cause of irreversible blindness worldwide, is usually diagnosed late due to poor understanding of the underlying genetic and molecular basis of disease development. We aim to develop Pdzd2-deficient mice as an animal model of glaucoma that would aid study of disease mechanism, and design of diagnostic and intervention strategies.