Longitudinal analysis of Epstein-Barr virus-specific T cells and NK cell responses in paediatric patients with infectious mononucleosis and post-transplant lymphoproliferative disorder


Grant Data
Project Title
Longitudinal analysis of Epstein-Barr virus-specific T cells and NK cell responses in paediatric patients with infectious mononucleosis and post-transplant lymphoproliferative disorder
Principal Investigator
Dr Chiang, Alan Kwok Shing   (Principal Investigator (PI))
Co-Investigator(s)
Dr Hui Kwai Fung   (Co-Investigator)
Duration
36
Start Date
2019-05-01
Amount
1197176
Conference Title
Longitudinal analysis of Epstein-Barr virus-specific T cells and NK cell responses in paediatric patients with infectious mononucleosis and post-transplant lymphoproliferative disorder
Presentation Title
Keywords
Epstein-Barr, Longitudinal, lymphoproliferative, mononucleosis, post-transplant, virus-specific
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
18170462
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2018
Status
On-going
Objectives
We aim to investigate the specific role(s) of distinct NK cell subsets and PFCs in the control of EBV infection through phenotypic and functional analyses of longitudinal samples of a large cohort of paediatric PTLD and IM patients.