Multi-scale single-cell optical imaging: architecture and biomedical applications

Professor Tsia, Kevin Kin Man   (Project Coordinator (PC))

Professor Lam Edmund Yin Mun   (Co-principal investigator)

Professor Wu Yilin   (Co-principal investigator)

Professor Wong Kenneth Kin Yip   (Co-principal investigator)

Professor Cheah Kathryn Song Eng   (Co-principal investigator)

Dr So Hayden Kwok Hay   (Co-principal investigator)

Professor Chan Godfrey Chi Fung   (Co-principal investigator)

48

2017-06-01

2021-05-31

8228300

Multi-scale single-cell optical imaging: architecture and biomedical applications

optofluidics, reconfigurable computing, ultrafast optical microscopy

Photonics,Imaging

Engineering (E)

C7047-16G

Collaborative Research Fund (CRF) - Group Research Project

2016

Completed

1. To develop an ultrafast multimodal optofluidic imaging prototype, built upon a new timestretch technology, for high-throughput quantitative phase and fluorescence single-cell imaging from which an unprecedented set of biophysical and biochemical markers can be retrieved. 2 . To integrate the optofluidic imaging system with a tailored computational hardware accelerator using field programmable gate array (FPGA) based reconfigurable computing for automated high-throughput single-cell image-derived analytics. 3. To apply the unified optofluidic imaging platform for multi-scale SCA experiments for the acquisition and definition of biophysical and biomolecular signatures of single cells in various heterogeneous populations.