A combined experimental and theoretical investigation on the AQP-dependent volumetric response and motility of lung and nasopharyngeal cancer cells

Dr Lin, Yuan   (Principal Investigator (PI))

Professor Jiang Hongyuan   (Co-Investigator)

Dr Ngan Roger Kai-Cheong   (Co-Investigator)

Dr Yip Timothy Tak-Chun   (Co-Investigator)

42

2017-01-01

675647

A combined experimental and theoretical investigation on the AQP-dependent volumetric response and motility of lung and nasopharyngeal cancer cells

Cancer, Cell Mechanics, Cell Motility, Water Channel Proteins

Mechanics and Dynamics

Engineering (E)

17257016

General Research Fund (GRF)

2016

Completed

1) To systematically examine the AQP-dependent response and death of different lung and nasopharyngeal cancer cells under osmotic stress; 2) To carefully monitor the AQP polarization-mediated migration of lung and nasopharyngeal tumor cells in the microchannel; 3) To model the transient and oscillatory movements of cells in a confined microenvironment.