Elucidating the therapeutic potential of neural stem cells with genetic manipulation of Sox9 expression following spinal cord injury

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Grant Data
Project Title
Elucidating the therapeutic potential of neural stem cells with genetic manipulation of Sox9 expression following spinal cord injury
Co-Investigator(s)
Professor Wu Wutian   (Co-Investigator)
Duration
42
Start Date
2016-11-01
Amount
903220
Conference Title
Elucidating the therapeutic potential of neural stem cells with genetic manipulation of Sox9 expression following spinal cord injury
Presentation Title
Keywords
ependymal layer, glial scar, neural stem cells, Sox9, spinal cord injury
Discipline
Stem Cell Biology,Transplantation
Panel
Biology and Medicine (M)
HKU Project Code
17123016
Grant Type
General Research Fund (GRF)
Funding Year
2016
Status
Completed
Objectives
1 Elucidate the role of Sox9 in the ependymal cells and resident astrocytes of adult mouse spinal cord 2 Assess the fate and responses of Sox9 knockout ependymal cells and resident astrocytes in spinal cord injury 3 Investigate the therapeutic potential of SOX9 knockdown-human neurospheres in rodent spinal cord injury model