Regulation and Function of Novel Histone Modifications

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Grant Data
Project Title
Regulation and Function of Novel Histone Modifications
Principal Investigator
Professor Li, Xiang David   (Project Coordinator (PC))
Co-Investigator(s)
Professor Cheung Tom Hiu Tung   (Co-principal investigator)
Dr Ishibashi Toyotaka   (Co-principal investigator)
Duration
36
Start Date
2016-05-01
Amount
5949593
Conference Title
Regulation and Function of Novel Histone Modifications
Presentation Title
Keywords
chemical biology, epigenetics, histone modification, posttranslational modification
Discipline
Biochemistry,Chemical Sciences
Panel
Physical Sciences (P)
HKU Project Code
C7029-15G
Grant Type
Collaborative Research Fund (CRF) - Group Research Project
Funding Year
2015
Status
Completed
Objectives
1. To identify and characterize enzymes that catalyze the addition and removal of histone Kcr and Ksucc marks. 2. To examine the influence of histone Ksucc on the compaction state of chromatin. 3. To elucidate the functional roles of histone Kcr in the regulation of gene expression.