Regulation and Function of Novel Histone Modifications


Grant Data
Project Title
Regulation and Function of Novel Histone Modifications
Principal Investigator
Dr Li, Xiang David   (Project coordinator)
Co-Investigator(s)
Dr Ishibashi Toyotaka   (Co-principal investigator)
Professor Cheung Tom Hiu Tung   (Co-principal investigator)
Duration
36
Start Date
2016-05-01
Completion Date
2019-04-30
Amount
5649631
Conference Title
Presentation Title
Keywords
histone modification, posttranslational modification, chemical biology, epigenetics
Discipline
Biochemistry,Chemical Sciences
Panel
Physical Sciences
Sponsor
RGC Collaborative Research Fund (CRF)
HKU Project Code
C7029-15G
Grant Type
Collaborative Research Fund (CRF) - Group Research Project
Funding Year
2015/2016
Status
On-going
Objectives
1. To identify and characterize enzymes that catalyze the addition and removal of histone Kcr and Ksucc marks. 2. To examine the influence of histone Ksucc on the compaction state of chromatin. 3. To elucidate the functional roles of histone Kcr in the regulation of gene expression.