Wavelength idler-signal-enhanced Raman scattering (WISERS) for applications in label-free super-resolution microscopy and spectroscopy

Professor Wong, Kenneth Kin Yip   (Principal Investigator (PI))

Professor Huser Thomas   (Co-principal investigator)

Dr Wei Xiaoming   (Co-Investigator)

Mr Hachmeister Henning Maximilian   (Co-Investigator)

24

2015-01-01

89600

Wavelength idler-signal-enhanced Raman scattering (WISERS) for applications in label-free super-resolution microscopy and spectroscopy

label-free super-resolution microscopy, spectroscopy, Wavelength idler-signal-enhanced Raman scattering, WISERS

Photonics

Engineering (E)

G-HKU708/14

Germany/Hong Kong Joint Research Scheme

2014

Completed

1. To develop and demonstrate a WISERS platform. We propose a wavelength idler-signal-enhanced Raman scattering (WISERS) platform, based on a one-pump optical parametric amplifier (OPA) configuration. This system will demonstrate the feasibility of achieving wideband optical amplification and wavelength conversion with low-noise and high-sensitivity performance around the 1000-nm wavelength window. Such kind of wideband wavelength conversion converts the CRS signals at the shorter wavelength up to the state-of-the-art telecom wavelength window with high-speed and low-noise detection. It is useful for microscopic and spectroscopic applications with high detection sensitivity, without compromising the high-speed due to the ultra-fast response time of WISERS. 2. To deploy the WISERS in a compact CRS system and demonstrate imaging applications. After demonstrating a prototype WISERS platform as summarized in the previous section, we will explore the feasibility of amplifying and converting the CRS signals to be detected by a high-speed and high-sensitivity detector. Our WISERS architecture is designed to capture these advantages which are critical attributes for next-generation biophotonic systems.