Polyamine/Let-7 signaling in embryo implantation and diapause
Grant Data
Project Title
Polyamine/Let-7 signaling in embryo implantation and diapause
Principal Investigator
Professor Yeung, William Shu Biu
(Principal Investigator (PI))
Co-Investigator(s)
Professor Murphy Bruce Daniel
(Co-Investigator)
Dr Lee Calvin Kai Fai
(Co-Investigator)
Dr Liu Weimin
(Co-Investigator)
Duration
42
Start Date
2016-01-01
Amount
1012304
Conference Title
Polyamine/Let-7 signaling in embryo implantation and diapause
Presentation Title
Keywords
blastocyst, diapause, implantation, let-7, polyamines
Discipline
Reproduction
Panel
Biology and Medicine (M)
HKU Project Code
17107915
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 To study the action of polyamines on implantation/diapause. 2 To determine the roles of steroids in the production of polyamines and let-7/let-7 containing exosomes in mouse endometrial cells. 3 To study the roles of uterine polyamines and let-7 in implantation/diapause in vivo. 4 To study the roles of hCG on polyamines and let-7 expression and function in human endometrial cells in vitro.