Role of Tsg101 in the process of influenza virus assembly and release


Grant Data
Project Title
Role of Tsg101 in the process of influenza virus assembly and release
Principal Investigator
Dr Sanyal, Sumana   (Principal Investigator (PI))
Co-Investigator(s)
Professor Ploegh Hidde   (Co-Investigator)
Duration
24
Start Date
2015-11-01
Amount
759020
Conference Title
Role of Tsg101 in the process of influenza virus assembly and release
Presentation Title
Keywords
influenza, ISG15, post-translational modificatio, Tsg101, ubiquitin
Discipline
Cell Biology
Panel
Biology and Medicine (M)
HKU Project Code
17113915
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 Examine whether Tsg101 plays a role as a general host factor in the intracellular transport of influenza viruses 2 Mechanism of Tsg101 regulation by post-translational modification during virus infection 3 Large scale proteomic/RNA seq analyses of Tsg101 positive vesicles to identify host factors that follow the same route