Semaphorin and perineuronal nets regulate developmental plasticity of central vestibular circuitry
Grant Data
Project Title
Semaphorin and perineuronal nets regulate developmental plasticity of central vestibular circuitry
Principal Investigator
Professor Chan, Ying Shing
(Principal Investigator (PI))
Co-Investigator(s)
Professor Shum Daisy Kwok Yan
(Co-Investigator)
Professor Yung Wing Ho
(Co-Investigator)
Duration
30
Start Date
2015-10-01
Amount
975758
Conference Title
Semaphorin and perineuronal nets regulate developmental plasticity of central vestibular circuitry
Presentation Title
Keywords
Learning and memory, Perineuronal nets, Semaphorin, Synaptic plasticity, Vestibular system
Discipline
Neurobiology and Neuromedicine
Panel
Biology and Medicine (M)
HKU Project Code
17125115
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 To study the effects of semaphorin 3A on synaptic transmission at vestibular interneurons before, and after the formation of perineuronal nets. 2 To find effects of remodeling chondroitin sulfation on the gradient of semaphorin 3A as presented to signaling receptor complexes for the maturation of negative geotaxis.