The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia
Grant Data
Project Title
The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia
Principal Investigator
Dr Chiu, Chi Ngong
(Principal Investigator (PI))
Co-Investigator(s)
Dr Lee Cheuk Lun
(Co-Investigator)
Professor Wong Alice Sze Tsai
(Co-Investigator)
Duration
36
Start Date
2015-10-01
Amount
1064451
Conference Title
The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia
Presentation Title
Keywords
decidual natural killer cell, extravillous trophoblast, glycodelin-A, placental vascular remodeling, preeclampsia
Discipline
Reproduction
Panel
Biology and Medicine (M)
HKU Project Code
17122415
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 To study the effect of glycodelin-A on decidual natural killer cell-mediated vascular remodeling 2 To study the regulatory role of decidual natural killer cells on the vascular remodeling activity of trophoblast and its association with glycodelin-A 3 To study the effect of glycodelin-A on the expression of activating receptors in decidual natural killer cell 4 To investigate the mechanism of glycodelin-A action on decidual natural killer cell 5 To determine the expression of glycodelin-A and its receptor in pregnancy complicated by preeclampsia