The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia


Grant Data
Project Title
The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia
Principal Investigator
Dr Chiu, Chi Ngong   (Principal investigator)
Co-Investigator(s)
Professor Wong Alice Sze Tsai   (Co-Investigator)
Dr Lee Cheuk Lun   (Co-Investigator)
Duration
36
Start Date
2015-10-01
Completion Date
2018-09-30
Amount
1064451
Conference Title
Presentation Title
Keywords
glycodelin-A, decidual natural killer cell, extravillous trophoblast, placental vascular remodeling, preeclampsia
Discipline
Reproduction
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17122415
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To study the regulatory role of decidual natural killer cells on the vascular remodeling activity of trophoblast and its association with glycodelin-A 3 To study the effect of glycodelin-A on the expression of activating receptors in decidual natural killer cell 4 To investigate the mechanism of glycodelin-A action on decidual natural killer cell 5 To determine the expression of glycodelin-A and its receptor in pregnancy complicated by preeclampsia