Compression-induced actin protrusions (CAPs) in human mesenchymal stem cells - Understanding the mechanisms of mechanoregulation

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Grant Data
Project Title
Compression-induced actin protrusions (CAPs) in human mesenchymal stem cells - Understanding the mechanisms of mechanoregulation
Principal Investigator
Professor Chan, Barbara Pui   (Principal Investigator (PI))
Co-Investigator(s)
Professor Lam Herny HN   (Co-Investigator)
Duration
36
Start Date
2016-01-01
Amount
1190986
Conference Title
Compression-induced actin protrusions (CAPs) in human mesenchymal stem cells - Understanding the mechanisms of mechanoregulation
Presentation Title
Keywords
actin cytoskeleton, mechanoregulation, mesenchymal stem cell
Discipline
Biomedical Engineering
Panel
Biology and Medicine (M)
HKU Project Code
17128315
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 To study the molecular signature of the CAPs; 2 To study the major signaling pathways regulating the formation of the CAPs; 3 To study the functional significance of the CAPs in mediating loading-induced cell alignment.