Method and software tool for estimating and dissecting the heritability of complex diseases


Grant Data
Project Title
Method and software tool for estimating and dissecting the heritability of complex diseases
Principal Investigator
Professor Sham, Pak Chung   (Principal investigator)
Co-Investigator(s)
Dr Li Miaoxin   (Co-Investigator)
Dr Cherny Stacey Shawn   (Co-Investigator)
Duration
36
Start Date
2015-11-01
Completion Date
2018-10-31
Amount
1167288
Conference Title
Presentation Title
Keywords
Diseases, Genome, SNP, Heritability, Method
Discipline
Genomic Medicine
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17128515
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To extend this method for bivariate analysis of two phenotypes, to quantify the total shared variance explained by a set of correlated genetic variants. 3 To implement this methodology into a convenient web-based software.