Likelihood methods for assessing association and parent-of-origin effects using case-control pedigrees
Professor Fung, Tony Wing Kam (Principal investigator)
statistical genetics, genetic epidemiology, genomic imprinting, association studies
Biology and Medicine (M)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
2 To derive powerful statistical tests for association and parent-of-origin effects for quantitative traits and in the X-chromosome. 3 To apply the proposed methods to analyze real data such as for rheumatoid arthritis in which significant imprinting effects have been observed.