Likelihood methods for assessing association and parent-of-origin effects using case-control pedigrees


Grant Data
Project Title
Likelihood methods for assessing association and parent-of-origin effects using case-control pedigrees
Principal Investigator
Professor Fung, Tony Wing Kam   (Principal investigator)
Duration
30
Start Date
2015-09-01
Completion Date
2018-02-28
Amount
600000
Conference Title
Presentation Title
Keywords
statistical genetics, genetic epidemiology, genomic imprinting, association studies
Discipline
Genetic Disease
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17301715
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To derive powerful statistical tests for association and parent-of-origin effects for quantitative traits and in the X-chromosome. 3 To apply the proposed methods to analyze real data such as for rheumatoid arthritis in which significant imprinting effects have been observed.