Novel Pituitary Actions of Neurokinin B (NKB) and NKB-Related Peptide in Fish Model: TAC3/NK3R System and its Interaction with Insulin-like Growth Factor in Somatolactin α Regulation in Carp Pituitary Cells
Professor Wong, Anderson On Lam (Principal investigator)
Neurokinin B, Somatolactin, Insulin-like Growth Factor, Pituitary, Fish
Biology and Medicine (M)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
2 To establish the role of carp NKBb as a novel antagonist for NK3R expressed in the carp pituitary and unveil the structural determinant in its C-terminal signature motif responsible for this antagonistic effect 3 To examine the role of NK3R expression and functional crosstalk in signal transduction for NK3R and IGF-I receptor in IGF potentiation of SLα expression in carp pituitary cells induced by TAC3 gene products.