Transcriptomic and proteomic analyses of exopolysaccharide producing dairy starter Streptococcus thermophilus ASCC 1275
Grant Data
Project Title
Transcriptomic and proteomic analyses of exopolysaccharide producing dairy starter Streptococcus thermophilus ASCC 1275
Principal Investigator
Professor Shah, Nagendra
(Principal Investigator (PI))
Co-Investigator(s)
Dr Lo Clive Sze Chung
(Co-Investigator)
Duration
48
Start Date
2015-09-01
Amount
834353
Conference Title
Transcriptomic and proteomic analyses of exopolysaccharide producing dairy starter Streptococcus thermophilus ASCC 1275
Presentation Title
Keywords
dairy fermentation, Exopolysaccharide, Proteomic analysis, Streptococcus thermophilus, Transcriptomic analysis
Discipline
Food Science
Panel
Biology and Medicine (M)
HKU Project Code
17105315
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 The objectives of this project are: to carry out transcriptomic and proteomic analyses of S. thermophilus under different growth conditions to identify key regulatory genes and associated genes in regulating EPS production; 2 to examine whether enhancing these key regulatory genes including the genes from eps gene cluster revealed from the omics studies in step (i) will increase EPS production and the quantity of EPS during milk fermentation by S. thermophilus ASCC 1275; 3 to carry out preliminary idenitication of essential nutrients, such as amino acids and carbohydrates (glucose, galactose, lactose) for EPS production; and 4 to carry out preliminary characterization of EPS produced from S. thermophilus 1275.