Development of encapuslated stem cells formed into a 3D complex transplantable device using microfluidic technology


Grant Data
Project Title
Development of encapuslated stem cells formed into a 3D complex transplantable device using microfluidic technology
Principal Investigator
Dr Botelho, Michael George   (Principal investigator)
Co-Investigator(s)
Dr Shum Ho Cheung   (Co-Investigator)
Dr Green David William   (Co-Investigator)
Duration
30
Start Date
2015-05-29
Completion Date
2017-11-28
Amount
82600
Conference Title
Presentation Title
Keywords
Stem cell, tissue engineering, Microfluidics, bone regeneration
Discipline
Dentistry,Stem Cell Biology
Panel
Dentistry
Sponsor
Block Grant Earmarked for Research (104)
HKU Project Code
201411159175
Grant Type
Seed Fund for Basic Research
Funding Year
2014/2015
Status
On-going
Objectives
1. To evaluate the influence of different ratio of col/HA on porosity parameters of produced gradient porous scaffold. 2. To evaluate the influence of different quenching rates on porosity parameters of produced gradient porous scaffold. 3. To analyze the in vitro cellular response of hMSC on gradient porous scaffold of various range of porosity parameters. 4. To explain the relationship between cellular behavior and porosity parameters in an attempt to define optimum porosity range for enhanced bone regeneration.