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- Publisher Website: 10.1016/j.optlaseng.2023.107964
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Article: FMMAS-OCT: Aberration correction for high-resolution cellular imaging
Title | FMMAS-OCT: Aberration correction for high-resolution cellular imaging |
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Authors | |
Keywords | Forward model High resolution Multiple aperture synthesis Optical coherence tomography |
Issue Date | 1-Mar-2024 |
Publisher | Elsevier |
Citation | Optics and Lasers in Engineering, 2024, v. 174 How to Cite? |
Abstract | In optical coherence tomography (OCT), spatial resolution and signal strength often suffer due to aberrations from both the imaging system and the sample. In this work, we introduce a novel method, FMMAS (Forward-Model Multiple Aperture Synthesis), which effectively compensates for these aberrations. It combines forward-model (FM) based method for transverse resolution restoration and multiple aperture synthesis (MAS) to mitigate depth domain aberrations. Our proof-of-concept experiment demonstrates a significant improvement in the mean transverse full width at half maximum (FWHM) of microparticles by 46.1 %. Compared to original OCT and FM method, FMMAS produces sharper, 'pencil beam'-like imaging, resolving cell nuclei in swine esophagus ex vivo and human blood cells in vivo, suggesting a potential for significant enhancements in OCT image quality. |
Persistent Identifier | http://hdl.handle.net/10722/347133 |
ISSN | 2023 Impact Factor: 3.5 2023 SCImago Journal Rankings: 1.009 |
DC Field | Value | Language |
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dc.contributor.author | Ge, Xin | - |
dc.contributor.author | He, Jin | - |
dc.contributor.author | Chen, Si | - |
dc.contributor.author | Ni, Guangming | - |
dc.contributor.author | Xiong, Qiaozhou | - |
dc.contributor.author | Yang, Jielong | - |
dc.contributor.author | Yu, Lequan | - |
dc.contributor.author | Liu, Linbo | - |
dc.contributor.author | Bo, En | - |
dc.date.accessioned | 2024-09-18T00:30:33Z | - |
dc.date.available | 2024-09-18T00:30:33Z | - |
dc.date.issued | 2024-03-01 | - |
dc.identifier.citation | Optics and Lasers in Engineering, 2024, v. 174 | - |
dc.identifier.issn | 0143-8166 | - |
dc.identifier.uri | http://hdl.handle.net/10722/347133 | - |
dc.description.abstract | <p>In optical coherence tomography (OCT), spatial resolution and signal strength often suffer due to aberrations from both the imaging system and the sample. In this work, we introduce a novel method, FMMAS (Forward-Model Multiple Aperture Synthesis), which effectively compensates for these aberrations. It combines forward-model (FM) based method for transverse resolution restoration and multiple aperture synthesis (MAS) to mitigate depth domain aberrations. Our proof-of-concept experiment demonstrates a significant improvement in the mean transverse full width at half maximum (FWHM) of microparticles by 46.1 %. Compared to original OCT and FM method, FMMAS produces sharper, 'pencil beam'-like imaging, resolving cell nuclei in swine esophagus ex vivo and human blood cells in vivo, suggesting a potential for significant enhancements in OCT image quality.</p> | - |
dc.language | eng | - |
dc.publisher | Elsevier | - |
dc.relation.ispartof | Optics and Lasers in Engineering | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Forward model | - |
dc.subject | High resolution | - |
dc.subject | Multiple aperture synthesis | - |
dc.subject | Optical coherence tomography | - |
dc.title | FMMAS-OCT: Aberration correction for high-resolution cellular imaging | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.optlaseng.2023.107964 | - |
dc.identifier.scopus | eid_2-s2.0-85179583940 | - |
dc.identifier.volume | 174 | - |
dc.identifier.eissn | 1873-0302 | - |
dc.identifier.issnl | 0143-8166 | - |