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- Publisher Website: 10.3201/eid2510.190130
- Scopus: eid_2-s2.0-85072366595
- PMID: 31423971
- WOS: WOS:000490017300002
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Article: Transmissibility of MERS-CoV Infection in Closed Setting, Riyadh, Saudi Arabia, 2015
Title | Transmissibility of MERS-CoV Infection in Closed Setting, Riyadh, Saudi Arabia, 2015 |
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Authors | |
Keywords | adult asthma breast cancer diabetes mellitus enzyme linked immunosorbent assay |
Issue Date | 2019 |
Publisher | US Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm |
Citation | Emerging Infectious Diseases, 2019, v. 25 n. 10, p. 1802-1809 How to Cite? |
Abstract | To investigate a cluster of Middle East respiratory syndrome (MERS) cases in a women-only dormitory in Riyadh, Saudi Arabia, in October 2015, we collected epidemiologic information, nasopharyngeal/oropharyngeal swab samples, and blood samples from 828 residents during November 2015 and December 2015-January 2016. We found confirmed infection for 19 (8 by reverse transcription PCR and 11 by serologic testing). Infection attack rates varied (2.7%-32.3%) by dormitory building. No deaths occurred. Independent risk factors for infection were direct contact with a confirmed case-patient and sharing a room with a confirmed case-patient; a protective factor was having an air conditioner in the bedroom. For 9 women from whom a second serum sample was collected, antibodies remained detectable at titers >1:20 by pseudoparticle neutralization tests (n = 8) and 90% plaque-reduction neutralization tests (n = 2). In closed high-contact settings, MERS coronavirus was highly infectious and pathogenicity was relatively low. |
Persistent Identifier | http://hdl.handle.net/10722/279420 |
ISSN | 2023 Impact Factor: 7.2 2023 SCImago Journal Rankings: 2.117 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Van Kerkhove, MDV | - |
dc.contributor.author | Alaswad, S | - |
dc.contributor.author | Assiri, A | - |
dc.contributor.author | Perera, RAPM | - |
dc.contributor.author | Peiris, M | - |
dc.contributor.author | El Bushra, HE | - |
dc.contributor.author | BinSaeed, AA | - |
dc.date.accessioned | 2019-11-01T07:17:01Z | - |
dc.date.available | 2019-11-01T07:17:01Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Emerging Infectious Diseases, 2019, v. 25 n. 10, p. 1802-1809 | - |
dc.identifier.issn | 1080-6040 | - |
dc.identifier.uri | http://hdl.handle.net/10722/279420 | - |
dc.description.abstract | To investigate a cluster of Middle East respiratory syndrome (MERS) cases in a women-only dormitory in Riyadh, Saudi Arabia, in October 2015, we collected epidemiologic information, nasopharyngeal/oropharyngeal swab samples, and blood samples from 828 residents during November 2015 and December 2015-January 2016. We found confirmed infection for 19 (8 by reverse transcription PCR and 11 by serologic testing). Infection attack rates varied (2.7%-32.3%) by dormitory building. No deaths occurred. Independent risk factors for infection were direct contact with a confirmed case-patient and sharing a room with a confirmed case-patient; a protective factor was having an air conditioner in the bedroom. For 9 women from whom a second serum sample was collected, antibodies remained detectable at titers >1:20 by pseudoparticle neutralization tests (n = 8) and 90% plaque-reduction neutralization tests (n = 2). In closed high-contact settings, MERS coronavirus was highly infectious and pathogenicity was relatively low. | - |
dc.language | eng | - |
dc.publisher | US Department of Health and Human Services, Centers for Disease Control and Prevention. The Journal's web site is located at http://www.cdc.gov/ncidod/EID/index.htm | - |
dc.relation.ispartof | Emerging Infectious Diseases | - |
dc.subject | adult | - |
dc.subject | asthma | - |
dc.subject | breast cancer | - |
dc.subject | diabetes mellitus | - |
dc.subject | enzyme linked immunosorbent assay | - |
dc.title | Transmissibility of MERS-CoV Infection in Closed Setting, Riyadh, Saudi Arabia, 2015 | - |
dc.type | Article | - |
dc.identifier.email | Perera, RAPM: mahenp@hku.hk | - |
dc.identifier.email | Peiris, M: malik@hkucc.hku.hk | - |
dc.identifier.authority | Perera, RAPM=rp02500 | - |
dc.identifier.authority | Peiris, M=rp00410 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3201/eid2510.190130 | - |
dc.identifier.pmid | 31423971 | - |
dc.identifier.pmcid | PMC6759265 | - |
dc.identifier.scopus | eid_2-s2.0-85072366595 | - |
dc.identifier.hkuros | 308603 | - |
dc.identifier.volume | 25 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1802 | - |
dc.identifier.epage | 1809 | - |
dc.identifier.isi | WOS:000490017300002 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1080-6040 | - |