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Conference Paper: Neural activity temporal pattern dictates the long-range brain-wide propagation pathways: An optogenetic fMRI study
Title | Neural activity temporal pattern dictates the long-range brain-wide propagation pathways: An optogenetic fMRI study |
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Authors | |
Issue Date | 2019 |
Publisher | International Society for Magnetic Resonance in Medicine. |
Citation | The 27th Annual Meeting & Exhibition of International Society for Magnetic Resonance in Medicine (ISMRM), Montreal, Canada, 11-16 May 2019 , paper 0202 How to Cite? |
Abstract | The current overarching challenge in neuroscience is to establish an integrated understanding of the brain networks, particularly the spatiotemporal patterns of neural activities that give rise to functions and behavior. fMRI provides the most versatile neuroimaging platform for mapping large-scale activities in vivo. However, on its own, many important details of the underlying network activities remain unresolved. Here, we employed fMRI in combination with pulsed optogenetic stimulation paradigms to probe the spatiotemporal dynamics and functions of the well-defined topographically-organized somatosensory thalamo-cortical network. We reveal unique long-range propagation pathways that are dictated by distinct neural activity temporal patterns initiated from the thalamus. |
Description | Scientific Session: fMRI: Multimodal - Oral - fMRI - no. 0202 |
Persistent Identifier | http://hdl.handle.net/10722/278719 |
DC Field | Value | Language |
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dc.contributor.author | Leong, TL | - |
dc.contributor.author | Wang, X | - |
dc.contributor.author | Dong, CM | - |
dc.contributor.author | Chan, RW | - |
dc.contributor.author | Wu, EX | - |
dc.date.accessioned | 2019-10-21T02:12:45Z | - |
dc.date.available | 2019-10-21T02:12:45Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | The 27th Annual Meeting & Exhibition of International Society for Magnetic Resonance in Medicine (ISMRM), Montreal, Canada, 11-16 May 2019 , paper 0202 | - |
dc.identifier.uri | http://hdl.handle.net/10722/278719 | - |
dc.description | Scientific Session: fMRI: Multimodal - Oral - fMRI - no. 0202 | - |
dc.description.abstract | The current overarching challenge in neuroscience is to establish an integrated understanding of the brain networks, particularly the spatiotemporal patterns of neural activities that give rise to functions and behavior. fMRI provides the most versatile neuroimaging platform for mapping large-scale activities in vivo. However, on its own, many important details of the underlying network activities remain unresolved. Here, we employed fMRI in combination with pulsed optogenetic stimulation paradigms to probe the spatiotemporal dynamics and functions of the well-defined topographically-organized somatosensory thalamo-cortical network. We reveal unique long-range propagation pathways that are dictated by distinct neural activity temporal patterns initiated from the thalamus. | - |
dc.language | eng | - |
dc.publisher | International Society for Magnetic Resonance in Medicine. | - |
dc.relation.ispartof | 2019 Proceedings of International Society for Magnetic Resonance in Medicine (ISMRM) Annual Meeting | - |
dc.title | Neural activity temporal pattern dictates the long-range brain-wide propagation pathways: An optogenetic fMRI study | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Leong, TL: tlleong@hku.hk | - |
dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
dc.identifier.authority | Leong, TL=rp02483 | - |
dc.identifier.authority | Wu, EX=rp00193 | - |
dc.identifier.hkuros | 307703 | - |
dc.identifier.spage | 0202 | - |
dc.identifier.epage | 0202 | - |
dc.publisher.place | United States | - |