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Article: Chemotherapy for non-metastatic high-grade osteosarcoma of extremity - Is neoadjuvant better than adjuvant?

TitleChemotherapy for non-metastatic high-grade osteosarcoma of extremity - Is neoadjuvant better than adjuvant?
Authors
KeywordsChemotherapy
Neoadjuvant therapy
Osteosarcoma
Adjuvant
Extremeties
Issue Date2003
Citation
Journal of the Hong Kong College of Radiologists, 2003, v. 6, n. 1, p. 7-14 How to Cite?
AbstractThe addition of adjuvant or neoadjuvant chemotherapy to surgery revolutionises the treatment of high-grade non-metastatic osteosarcoma of the extremities. Overall 5-year survival of more than 50% to 60% is now a realistic achievable goal. Neoadjuvant chemotherapy possesses the theoretical advantages of optimising surgical results, providing early treatment of micrometastases, allowing histological assessment of chemotherapy, and customising postoperative chemotherapy. In this paper, the literature is reviewed to explore the existence of any comparative benefit of neoadjuvant over adjuvant chemotherapy for this disease entity.
Persistent Identifierhttp://hdl.handle.net/10722/251602

 

DC FieldValueLanguage
dc.contributor.authorNgan, R. K C-
dc.date.accessioned2018-03-08T05:00:26Z-
dc.date.available2018-03-08T05:00:26Z-
dc.date.issued2003-
dc.identifier.citationJournal of the Hong Kong College of Radiologists, 2003, v. 6, n. 1, p. 7-14-
dc.identifier.urihttp://hdl.handle.net/10722/251602-
dc.description.abstractThe addition of adjuvant or neoadjuvant chemotherapy to surgery revolutionises the treatment of high-grade non-metastatic osteosarcoma of the extremities. Overall 5-year survival of more than 50% to 60% is now a realistic achievable goal. Neoadjuvant chemotherapy possesses the theoretical advantages of optimising surgical results, providing early treatment of micrometastases, allowing histological assessment of chemotherapy, and customising postoperative chemotherapy. In this paper, the literature is reviewed to explore the existence of any comparative benefit of neoadjuvant over adjuvant chemotherapy for this disease entity.-
dc.languageeng-
dc.relation.ispartofJournal of the Hong Kong College of Radiologists-
dc.subjectChemotherapy-
dc.subjectNeoadjuvant therapy-
dc.subjectOsteosarcoma-
dc.subjectAdjuvant-
dc.subjectExtremeties-
dc.titleChemotherapy for non-metastatic high-grade osteosarcoma of extremity - Is neoadjuvant better than adjuvant?-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.scopuseid_2-s2.0-0038204840-
dc.identifier.volume6-
dc.identifier.issue1-
dc.identifier.spage7-
dc.identifier.epage14-

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