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Article: Potential Neuroprotective Effects of Adiponectin in Alzheimer's Disease

TitlePotential Neuroprotective Effects of Adiponectin in Alzheimer's Disease
Authors
Ng, CLChan, KH
KeywordsAdiponectin
Alzheimer’s disease
Amyloid-β
Cognitive impairments
Issue Date2017
PublisherMolecular Diversity Preservation International. The Journal's web site is located at http://www.mdpi.org/ijms
Citation
International Journal of Molecular Sciences, 2017, v. 18, p. 592:1-13 How to Cite?
DOI: http://dx.doi.org/10.3390/ijms18030592
AbstractThe adipocyte-secreted protein adiponectin (APN) has several protective functions in the peripheral tissues including insulin sensitizing, anti-inflammatory and anti-oxidative effects that may benefit neurodegenerative diseases such as Alzheimer's disease (AD). In addition, dysregulation of cerebral insulin sensitivities and signaling activities have been implicated in AD. Emerging insights into the mechanistic roles of adiponectin and AD highlight the potential therapeutic effects for AD through insulin signaling.
Persistent Identifierhttp://hdl.handle.net/10722/240932
ISSN
1422-0067
2023 Impact Factor: 4.9
2023 SCImago Journal Rankings: 1.179
ISI Accession Number ID
WOS:000396253700123

 

DC FieldValueLanguage
dc.contributor.authorNg, CL-
dc.contributor.authorChan, KH-
dc.date.accessioned2017-05-22T09:19:42Z-
dc.date.available2017-05-22T09:19:42Z-
dc.date.issued2017-
dc.identifier.citationInternational Journal of Molecular Sciences, 2017, v. 18, p. 592:1-13-
dc.identifier.issn1422-0067-
dc.identifier.urihttp://hdl.handle.net/10722/240932-
dc.description.abstractThe adipocyte-secreted protein adiponectin (APN) has several protective functions in the peripheral tissues including insulin sensitizing, anti-inflammatory and anti-oxidative effects that may benefit neurodegenerative diseases such as Alzheimer's disease (AD). In addition, dysregulation of cerebral insulin sensitivities and signaling activities have been implicated in AD. Emerging insights into the mechanistic roles of adiponectin and AD highlight the potential therapeutic effects for AD through insulin signaling.-
dc.languageeng-
dc.publisherMolecular Diversity Preservation International. The Journal's web site is located at http://www.mdpi.org/ijms-
dc.relation.ispartofInternational Journal of Molecular Sciences-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAdiponectin-
dc.subjectAlzheimer’s disease-
dc.subjectAmyloid-β-
dc.subjectCognitive impairments-
dc.titlePotential Neuroprotective Effects of Adiponectin in Alzheimer's Disease-
dc.typeArticle-
dc.identifier.emailNg, CL: royclng@hku.hk-
dc.identifier.emailChan, KH: koonho@hku.hk-
dc.identifier.authorityChan, KH=rp00537-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/ijms18030592-
dc.identifier.scopuseid_2-s2.0-85014936928-
dc.identifier.hkuros272292-
dc.identifier.volume18-
dc.identifier.spage592:1-
dc.identifier.epage13-
dc.identifier.isiWOS:000396253700123-
dc.publisher.placeSwitzerland-
dc.identifier.issnl1422-0067-

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