Multimodal investigations of liquid biopsy in detection and clinical management of hepatocellular carcinoma
Grant Data
Project Title
Multimodal investigations of liquid biopsy in detection and clinical management of hepatocellular carcinoma
Principal Investigator
Professor Ho, Daniel Wai Hung
(Principal Investigator (PI))
Co-Investigator(s)
Professor Ng Irene Oi Lin
(Co-principal investigator)
Dr Tsui Yu Man
(Co-principal investigator)
Duration
36
Start Date
2023-09-01
Amount
1498888
Conference Title
Multimodal investigations of liquid biopsy in detection and clinical management of hepatocellular carcinoma
Keywords
Liquid biopsy, Cell-free DNA, Circulating tumor DNA, cfDNA, ctDNA
Discipline
Biology and Medicine
Panel
Biology and Medicine (M)
HKU Project Code
10212956
Grant Type
Health and Medical Research Fund 2021
Funding Year
2023
Status
On-going
Objectives
Hepatocellular carcinoma (HCC) is often detected at advanced stage and inoperable, with systemic drug treatments being the major treatment options. Liquid-biopsy strategies e.g. circulating tumor DNA (ctDNA) have attractive advantages as compared to the traditional tissue-biopsy. Therefore, it is necessary to evaluate the translational applications of liquid-biopsy in early detection and clinical management of HCC.