Surveillance of humoral and cellular immunity against COVID-19 among older adults with comorbidities in Hong Kong
Grant Data
Project Title
Surveillance of humoral and cellular immunity against COVID-19 among older adults with comorbidities in Hong Kong
Co-Investigator(s)
Professor Hung Fan Ngai Ivan
(Co-principal investigator)
Professor Chen Zhiwei
(Co-principal investigator)
Professor Yuen Jacqueline Kwan Yuk
(Co-principal investigator)
Duration
24
Start Date
2023-05-02
Amount
1494412
Conference Title
Surveillance of humoral and cellular immunity against COVID-19 among older adults with comorbidities in Hong Kong
Keywords
COVID-19, Neutralizing antibody, T cell immunity, Geriatrics, Vaccine
Discipline
Others - Medicine, Dentistry and Health
Panel
Biology and Medicine (M)
HKU Project Code
22210852
Grant Type
Health and Medical Research Fund 2021
Funding Year
2022
Status
On-going
Objectives
Older adults with comorbidities are the greatest risk of hospitalization or death due to COVID-19. The overall aim is to assess humoral antibody and cellular immunity among this vulnerable population. Specific objectives are: 1: To determine the neutralizing antibody activity and T cell immunity against SARS-CoV-2 Omicron variant and emerging variants among older adults with comorbidities; 2: To investigate the risk factors associated with poor neutralizing antibody and T cell response