Functional interrogation of non-coding regulatory regions identified from Hirschsprung disease patients
Grant Data
Project Title
Functional interrogation of non-coding regulatory regions identified from Hirschsprung disease patients
Principal Investigator
Dr Song, You-qiang
(Principal Investigator (PI))
Co-Investigator(s)
Emeritus Professor Cheah Kathryn Song Eng
(Co-Investigator)
Dr Tang Sze Man
(Co-Investigator)
Emeritus Professor Tam Paul Kwong Hang
(Co-Investigator)
Duration
36
Start Date
2022-01-03
Amount
1424140
Conference Title
Functional interrogation of non-coding regulatory regions identified from Hirschsprung disease patients
Presentation Title
Keywords
Gene regulation, Hirschsprung disease, Mouse genetics, Non-coding regulatory
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
08191496
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2020
Status
On-going
Objectives
Determine the biological roles of non-coding regulatory elements identified from Hirschsprung disease (HSCR) patients during the development of the enteric nervous system (ENS) and how genetic variations affect their regulatory functions that lead to HSCR.