The role of adiponectin signalling in Tauopathy: implication of adiponectin receptor agonist as a therapeutic treatment for Tau-mediated neurodegeneration

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Grant Data
Project Title
The role of adiponectin signalling in Tauopathy: implication of adiponectin receptor agonist as a therapeutic treatment for Tau-mediated neurodegeneration
Principal Investigator
Professor Cheung, Raymond Tak Fai   (Principal Investigator (PI))
Co-Investigator(s)
Professor Chan Koon Ho   (Co-Investigator)
Dr Iyaswamy Ashok   (Co-Investigator)
Professor Li Min   (Co-Investigator)
Ng Roy Chun Laam   (Co-Investigator)
Duration
36
Start Date
2022-01-01
Amount
1493388
Conference Title
The role of adiponectin signalling in Tauopathy: implication of adiponectin receptor agonist as a therapeutic treatment for Tau-mediated neurodegeneration
Keywords
Adiponectin, AdipoRon, Alzheimer's disease, Cerebral insulin resistance, neurodegeneration, Tau
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
08193146
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2020
Status
On-going
Objectives
We aim to study the use of adipoRon as an oral therapeutic treatment for tauopathy by reducing neuroinflammation and insulin sensitization