Combined BiIA-SG and anti-TRABD2A antibody for HIV-1 Functional Cure

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Grant Data
Project Title
Combined BiIA-SG and anti-TRABD2A antibody for HIV-1 Functional Cure
Principal Investigator
Professor Chen, Zhiwei   (Principal Investigator (PI))
Duration
36
Start Date
2021-01-01
Amount
1195502
Conference Title
Combined BiIA-SG and anti-TRABD2A antibody for HIV-1 Functional Cure
Presentation Title
Keywords
BiIA-SG, bi-specific antibody, Functional Cure, HIV-1, TRABD2A
Discipline
Microbiology,Infection/Parasitology
Panel
Biology and Medicine (M)
HKU Project Code
17121420
Grant Type
General Research Fund (GRF)
Funding Year
2020
Status
On-going
Objectives
1 To determine the efficacy of combined BiIA-SG and TRABD2A-blocking antibody in treating HIV-1 latent infection as compared with their monotherapy 2 To determine the efficacy of combined cART and TRABD2A-depleting antibody in treating HIV-1 latent infection