Rapid development of anti-SARS-CoV-2 (2019-nCoV) vaccines and exploration of the feasibility of a Pancoronavirus vaccine

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Grant Data
Project Title
Rapid development of anti-SARS-CoV-2 (2019-nCoV) vaccines and exploration of the feasibility of a Pancoronavirus vaccine
Principal Investigator
Professor Huang, Jiandong   (Principal Investigator (PI))
Co-Investigator(s)
Professor Tong Yigang   (Co-Investigator)
Professor Li Xuechen   (Co-Investigator)
Duration
24
Start Date
2020-04-01
Amount
3202688
Conference Title
Rapid development of anti-SARS-CoV-2 (2019-nCoV) vaccines and exploration of the feasibility of a Pancoronavirus vaccine
Presentation Title
Keywords
anti-SARS-CoV-2 (2019-nCoV) vaccines, Pancoronavirus vaccine
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
COVID190117
Grant Type
Commissioned Research on the Novel Coronavirus Disease (COVID-19)
Funding Year
2019
Status
On-going
Objectives
1. Emergency anti-SARS-CoV-2 vaccine development based on (I) Spy-VLP platform; (ii) mRNA platform; (iii) DNA platform. 2. Preclinical testing of the protection efficacy of the rapid vaccine candidates, GMP production and preclinical toxicology testing (outsourcing to CRO with additional funding). 3. Development toward a pan-coronavirus vaccines against SARS-CoV, SARS-CoV-2 and MERS-CoV.