Molecular classification based on microsatellite instability and RAS pathway status as prognostic biomarkers for risk stratification of metastatic relapse in colon carcinoma patients
Grant Data
Project Title
Molecular classification based on microsatellite instability and RAS pathway status as prognostic biomarkers for risk stratification of metastatic relapse in colon carcinoma patients
Principal Investigator
Dr Ko, Josephine Mun Yee
(Principal Investigator (PI))
Co-Investigator(s)
Dr Chiang Chi Leung
(Co-Investigator)
Dr Lo Wing Ip Anthony
(Co-Investigator)
Dr Dai Wei
(Co-Investigator)
Emeritus Professor Lung Maria Li
(Co-Investigator)
Dr Lam Ka On
(Co-Investigator)
Duration
36
Start Date
2020-07-01
Amount
1499750
Conference Title
Molecular classification based on microsatellite instability and RAS pathway status as prognostic biomarkers for risk stratification of metastatic relapse in colon carcinoma patients
Keywords
Colorectal cancer, Liquid biopsies, metastatic relapse, molecular subtypes, Next generation sequencing, Prognostic biomarker
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
07181536
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2019
Status
On-going
Objectives
Objectives: To evaluate the prognostic value of six molecular classifications based on inflammatory, microsatellite instability (MSI) and Ras pathway status in stratifying patients with stage III colon cancer (CC) for metastatic relapse