Identification and characterization of SPINK6 as a novel host factor to restrict influenza A virus activation
Grant Data
Project Title
Identification and characterization of SPINK6 as a novel host factor to restrict influenza A virus activation
Principal Investigator
Dr Zhou, Jie
(Principal Investigator (PI))
Co-Investigator(s)
Professor Chen Honglin
(Co-Investigator)
Duration
36
Start Date
2020-04-01
Amount
1499999
Conference Title
Identification and characterization of SPINK6 as a novel host factor to restrict influenza A virus activation
Presentation Title
Keywords
HA cleavage, Influenza A virus, Protease inhibitor, Serine protease, viral growth
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
19180392
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2019
Status
On-going
Objectives
we aim to establish SPINK6 as a novel restriction factor against influenza virus activation via its inhibition of airway proteases.