Genetic study of adolescent idiopathic scoliosis in Chinese and functional analysis of a disease variant

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Grant Data
Project Title
Genetic study of adolescent idiopathic scoliosis in Chinese and functional analysis of a disease variant
Principal Investigator
Dr Song, You-qiang   (Principal Investigator (PI))
Co-Investigator(s)
Dr Cheung Jason Pui Yin   (Co-Investigator)
Dr Gao Bo   (Co-Investigator)
Duration
36
Start Date
2019-08-31
Completion Date
2022-08-30
Amount
892915
Conference Title
Genetic study of adolescent idiopathic scoliosis in Chinese and functional analysis of a disease variant
Keywords
adolescent idiopathic scoliosi, mouse model, mutation, WGS
Discipline
Genetic DiseaseOrthopaedics/Traumatology
Panel
Biology and Medicine (M)
HKU Project Code
17114519
Grant Type
General Research Fund (GRF)
Funding Year
2019
Status
Completed
Objectives
1) Characterize in vivo and in vitro the pathogenesis of the gene in AIS mice; 2) Genetic study of three new AIS families