Dysregulation of interleukin-18 receptor accessory protein in neutrophils of lupus nephritis patients – a pilot study

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Grant Data
Project Title
Dysregulation of interleukin-18 receptor accessory protein in neutrophils of lupus nephritis patients – a pilot study
Principal Investigator
Professor Lau, Wallace Chak Sing   (Principal Investigator (PI))
Co-Investigator(s)
Dr Chan Vera Sau Fong   (Co-Investigator)
Dr Lam Ian Kar Yin   (Co-Investigator)
Duration
15
Start Date
2019-06-01
Amount
100000
Conference Title
Dysregulation of interleukin-18 receptor accessory protein in neutrophils of lupus nephritis patients – a pilot study
Presentation Title
Keywords
Dysregulation, interleukin-18, lupus, nephritis, neutrophils, receptor
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
06172386
Grant Type
Health and Medical Research Fund - Mini Grant
Funding Year
2018
Status
Completed
Objectives
To characterise the dysregulated IL18RAP response in neutrophils in correlation with SLE disease; to evaluate the regulatory effect of IFN-α on neutrophil IL18RAP expression and function.