Targeting Human papillomavirus (HPV) negative cervical cancer
Grant Data
Project Title
Targeting Human papillomavirus (HPV) negative cervical cancer
Principal Investigator
Dr Wong, Gee Wan
(Principal Investigator (PI))
Co-Investigator(s)
Professor Cheung Annie Nga Yin
(Co-Investigator)
Dr Liu Si
(Co-Investigator)
Professor Ngan Hextan Yuen Sheung
(Co-Investigator)
Duration
24
Start Date
2018-07-01
Amount
1199384
Conference Title
Targeting Human papillomavirus (HPV) negative cervical cancer
Presentation Title
Keywords
ARID1A, Cervical cancer, HPV negative cervical, HPV test, Human papillomavirus
Discipline
Others - Medicine, Dentistry and Health
HKU Project Code
05162176
Grant Type
Health and Medical Research Fund - Full Grant
Funding Year
2017
Status
Completed
Objectives
This study aim to evaluate the impact of HPV status on clinical outcome of cervical cancer patients and the dependency of HPV-negative cervical cancer on the SWI/SNF chromatin remodeling pathway dysfunction. Pharmacological targeting of these pathways will also be explored as novel therapies of this subgroup of cervical cancer.