The regulatory role of placenta-derived extracellular vesicles on the differentiation and functions of human decidual macrophages

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Grant Data
Project Title
The regulatory role of placenta-derived extracellular vesicles on the differentiation and functions of human decidual macrophages
Principal Investigator
Professor Ng, Ernest Hung Yu   (Principal Investigator (PI))
Co-Investigator(s)
Dr Chiu Chi Ngong   (Co-Investigator)
Dr Lee Cheuk Lun   (Co-Investigator)
Duration
42
Start Date
2018-01-01
Amount
1008089
Conference Title
The regulatory role of placenta-derived extracellular vesicles on the differentiation and functions of human decidual macrophages
Presentation Title
Keywords
decidual macrophage, extracellular vesicle, extravillous trophoblast, placenta, preeclampsia
Discipline
Reproduction,Physiology
Panel
Biology and Medicine (M)
HKU Project Code
17118917
Grant Type
General Research Fund (GRF)
Funding Year
2017
Status
Completed
Objectives
1 To study the role of pEV in polarizing decidual macrophage differentiation. 2 To study the role of pEV on decidual macrophage-mediated functions. 3 To investigate the siglec-6 mediated binding of pEV and the mechanism for pEV-mediated decidual macrophage differentiation