The molecular regulations, roles, and clinical implications of hypoxia-induced porcupine in hepatocellular carcinoma

View Statistics Email Alert RSS Feed

Grant Data
Project Title
The molecular regulations, roles, and clinical implications of hypoxia-induced porcupine in hepatocellular carcinoma
Principal Investigator
Dr Wong, Carmen Chak Lui   (Principal Investigator (PI))
Co-Investigator(s)
Professor Ng Irene Oi Lin   (Co-Investigator)
Duration
36
Start Date
2018-01-01
Amount
1014736
Conference Title
The molecular regulations, roles, and clinical implications of hypoxia-induced porcupine in hepatocellular carcinoma
Presentation Title
Keywords
HCC, HIF, PORCN
Discipline
Cancer,Cell Biology
Panel
Biology and Medicine (M)
HKU Project Code
17117417
Grant Type
General Research Fund (GRF)
Funding Year
2017
Status
Completed
Objectives
1 To investigate the clinical significance of PORCN expression in human HCC 2 To elucidate the regulation of PORCN in HCC 3 To study the functions of the HIF/PORCN pathway in HCC 4 To evaluate the efficiency and efficacy of PORCN inhibitors in HCC treatment