HKU ResearcherPage: Srivastava, G

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Srivastava, Gopesh picture
Professor Srivastava, Gopesh
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Principal Investigator
Project Code Amount Title Funding Year
1 HKU 777312M 944972 Epigenetic silencing of the lymphocyte homing receptor CD44 in reactive germinal center B cells (GCB) and its activation in GCB-derived lymphomas by aberrant promoter hypomethylation 2012/2013
2 HKU 778511M 1120000 Molecular features and functional consequences of a novel recurrent t(14;20)(q32;q13.12)/IGHS?PRKCBP1 translocation in gastric and other B-cell non-Hodgkins lymphomas 2011/2012
3 HKU 776309M 1100000 Inactivation of the transcriptional repressor PRDM1 and imbalance in the expression of PRDM1 ?and ?isoforms in NK-cell malignancies, and their roles in the pathogenesis 2009/2010
4 HKU 775607M 1448992 Genetic and epigenetic mechanisms and clinicopathological significance of the silencing of a 6q22.33-q23.2 putative tumor suppressor PTPRK (protein tyrosine phosphatase, receptor type, kappa) gene in extranodal NK/T-cell lymphoma, nasal type 2007/2008
5 HKU 7627/06M 1229500 Therapeutic potential and mechanisms of antitumor activity of proteasome inhibitor bortezomib in extranodal NK/T-cell lymphoma, nasal type 2006/2007
6 HKU 7583/05M 902957 Molecular mechanisms and clinicopathological significance of the aberrant nuclear BCL10 expression and constitutive NF-[kappa]B activation in EBV-associated nasal NK/T-cell lymphoma 2005/2006
7 1264512 Characterization of the role of immunoglobulin heavy and light chain [kappa] and [lambda] gene translocations in the pathogenesis of gastric lymphoma 2004/2005
8 HKU 7448/04M 1351500 Role of CD44 and protein kinase C-binding protein 1, novel translocation partners of immunoglobulin heavy chain gene, in the pathogenesis of gastric lymphoma 2004/2005
9 HKU 7348/02M 528000 Immune escape mechanisms in EBV-associated nasal T/NK-cell lymphoma: mutations in pro-apoptotic genes 2002/2003
10 HKU 7072/99M 824320 Identification and characterization of heterologous promoters which deregulate the expression of BCL-6 oncogene in gastric high-grade lymphoma of MALT-type 1999/2000
11 HKU 7299/98M 645000 Mechanisms of immune evasion by the tumor cells of nasal T/NK-cell lymphoma 1998/1999
12 20000 Genetics studies on angiotensin-converting enzyme, clotting factors and apolipoproteins in cerebrovascular diseases 1994/1995
13 46000 Apolipoproteins genetic variations - role in atherosclerosis 1992/1993
14 307884 Effect of heme on the induction of mRNAs of apolipoproteins A-I, A-II and A-IV by porphyrinogenic drugs in rat liver and in human hepatoma HepG2 cell line 1989/1990
15 25000 Role of heme in the gene expression of peroxisomal B-oxidation enzymes 1989/1990

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