Grant: Role of retinoic acid inducible gene-1, toll-like receptor-3 and -8 in cytokine induction by influenza A H5N1 and pandemic H1N1 viruses in primary human cells

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Project Title
Role of retinoic acid inducible gene-1, toll-like receptor-3 and -8 in cytokine induction by influenza A H5N1 and pandemic H1N1 viruses in primary human cells
 
Principal Investigator Dr Hui Pui Yan (Principal investigator)
Co-Investigator(s) Cheung, Chung Yan (Co-Investigator)
Peiris, Joseph Sriyal Malik (Co-Investigator)
Chan, Michael Chi Wai (Co-Investigator)
Lee, Man Yan (Co-Investigator)
Chan, Wan Yi (Co-Investigator)
Project Code
10091062
 
Funding Year
2010/2011
 
Amount
995836
 
Panel Medicine
Start Date
01-11-2010
 
Expected Completion
30-04-2013
 
Status
On-going
 
Keywords Influenza A virus, H5N1, Toll-like receptors, RIG-1, Macrophage, Alveolar epithelial cell
Grant Type/Funding Scheme Research Fund for the Control of Infectious Diseases - Full Grants
Duration
30
 
Publication H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades
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