| Principal Investigator |
Ng, Irene Oi Lin
(Principal investigator)
|
| Co-Investigator(s) |
Fan, Sheung Tat
(Collaborator)
Poon, Ronnie Tung Ping
(Co-Investigator)
Huang, Jiandong
(Collaborator)
Jin, Dong-Yan
(Co-Investigator)
Guan, Xin-Yuan
(Co-Investigator)
Cheung, Siu Tim
(Co-Investigator)
Lai, Ching Lung
(Collaborator)
Ching, Yick Pang
(Co-Investigator)
Professor Poon Randy Yat Choi
(Collaborator)
Professor Lai Po Shan
(Collaborator)
Professor Ben-Neriah Yinon
(Collaborator)
Professor Mak Tak Wah
(Collaborator)
|
| Sponsor |
RGC Collaborative Research Fund (CRF)
|
| Grant Type/Funding Scheme |
Collaborative Research Fund (CRF) - Group Research Project
|
| Publication |
Activation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylation
|
| Publication |
Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma
|
| Publication |
Role and significance of focal adhesion proteins in hepatocellular carcinoma
|
| Publication |
Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion
|
| Publication |
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
|
| Publication |
Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma
|
| Publication |
Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma
|
| Publication |
Liver cancer stem cells: Implications for a new therapeutic target
|
| Publication |
Akt phosphorylation of deleted in liver cancer 1 abrogates its suppression of liver cancer tumorigenesis and metastasis
|
| Publication |
Deleted in liver cancer 2 suppresses cell growth via the regulation of the Raf-1-ERK1/2-p70S6K signalling pathway
|
| Publication |
Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma
|
| Publication |
N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H
|
| Publication |
Hepatocyte-specific activation of NF-κB does not aggravate chemical hepatocarcinogenesis in transgenic mice
|
| Publication |
Deregulation of microRNA expression occurs early and accumulates in early stages of HBV-associated multistep hepatocarcinogenesis
|
| Publication |
Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis
|
| Publication |
Loss of phosphatase and tensin homolog enhances cell invasion and migration through aKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance
|
| Publication |
CD24 + Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation
|
| Publication |
Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery
|
| Publication |
Granulin-epithelin precursor and ATP-dependent binding cassette (ABC)B5 regulate liver cancer cell chemoresistance
|
| Publication |
MiR-130b promotes CD133 + liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1
|
| Publication |
Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma
|
| Publication |
Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection
|
| Publication |
Sequential alterations of microRNA expression in hepatocellular carcinoma development and venous metastasis
|
| Publication |
Role of a novel splice variant of mitotic arrest deficient 1 (MAD1), MAD1β, in mitotic checkpoint control in liver cancer
|
| Publication |
Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation
|
| Publication |
Nuclear-targeted deleted in liver cancer 1 (DLC1) is less efficient in exerting its tumor suppressive activity both in vitro and in vivo
|
| Publication |
CD133 + liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling
|
| Publication |
Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma
|
