| Project Title |
Liver Transplantation Research Centre: A Multidisciplinary Study for Liver Graft Injury
|
| Principal Investigator |
Lo, Chung Mau
(Principal investigator)
|
| Co-Investigator(s) |
Man, Kwan
(Co-Investigator)
Guan, Xin-Yuan
(Co-Investigator)
Xu, Aimin
(Co-Investigator)
Professor Wong Nathalie
(Co-Investigator)
|
| Project Code |
|
| Funding Year |
|
| Amount |
|
| Panel |
Biology and Medicine (M)
|
| Start Date |
|
| Expected Completion |
|
| Status |
|
| Keywords |
Liver transplantation, Marginal graft injury, Surgical stress, Tumor microenvironment, Recurrence and Metastasis
|
| Discipline |
Surgical Research, Transplantation
|
| Sponsor |
RGC Collaborative Research Fund (CRF)
|
| Grant Type/Funding Scheme |
Collaborative Research Fund (CRF) - Group Research Project
|
| Duration |
|
| Publication |
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
|
| Publication |
Suppression of liver tumor growth and metastasis by adiponectin in nude mice through inhibition of tumor angiogenesis and downregulation of rho kinase/IFN-inducible protein 10/matrix metalloproteinase 9 signaling
|
| Publication |
Reduced CRYL1 expression in hepatocellular carcinoma confers cell growth advantages and correlates with adverse patient prognosis
|
| Publication |
Distinct mechanism of small-for-size fatty liver graft injury - Wnt4 signaling activates hepatic stellate cells
|
| Publication |
Molecular signature linked to acute phase injury and tumor invasiveness in small-for-size liver grafts
|
| Publication |
Occult hepatitis B virus infection of donor and recipient origin after liver transplantation despite nucleoside analogue prophylaxis
|
| Publication |
Activation of interleukin-6-induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration
|
| Publication |
Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion
|
| Publication |
Overexpression of matrix metalloproteinase-12 (MMP-12) correlates with poor prognosis of hepatocellular carcinoma
|
| Publication |
Proline-rich tyrosine kinase 2 (Pyk2) promotes cell motility of hepatocellular carcinoma through induction of epithelial to mesenchymal transition
|
| Publication |
Brain-derived neurotrophic factor promotes tumorigenesis via induction of neovascularization: Implication in hepatocellular carcinoma
|
| Publication |
Interleukin 17a promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression
|
| Publication |
Biology of hepatic cancer stem cells
|
| Publication |
MiR-130b promotes CD133 + liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1
|
| Publication |
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
|
| Publication |
The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma
|
| Publication |
Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice
|
| Publication |
Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development
|
| Publication |
Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma
|
| Publication |
FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells
|
