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Article: Antimicrobial stewardship program directed at broad-spectrum intravenous antibiotics prescription in a tertiary hospital

TitleAntimicrobial stewardship program directed at broad-spectrum intravenous antibiotics prescription in a tertiary hospital
Authors
KeywordsChemicals And Cas Registry Numbers
Issue Date2009
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/10096/index.htm
Citation
European Journal Of Clinical Microbiology And Infectious Diseases, 2009, v. 28 n. 12, p. 1447-1456 How to Cite?
AbstractThe antimicrobial stewardship program (ASP) is a major strategy to combat antimicrobial resistance and to limit its expenditure. We have improved on our existing ASP to implement a sustainable and cost-effective two-stage immediate concurrent feedback (ICF) model, in which the antimicrobial prescription is audited by two part-time infection control nurses at the first stage, followed by "physician ICF" at the second stage. In January 2005, an ASP focused on broad-spectrum intravenous antibiotics was implemented. All in-patients, except from the intensive care, bone marrow transplantation, liver transplantation, pediatric, and private units, being treated with broad-spectrum intravenous antibiotics were included. The compliance to ICF and "physician ICF", antibiotics usage density measured by expenditure and defined daily doses (DDD) were recorded and analyzed before and after the ASP. The overall conformance rate to antibiotic prescription guidelines was 79.4%, while the conformance to ICF was 83.8%. Antibiotics consumption reduced from 73.06 (baseline, year 2004) to 64.01 (year 2007) per 1,000 patient bed-day-occupancy. Our model can be easily applied even in the clinical setting of limited resources. © 2009 Springer-Verlag.
Persistent Identifierhttp://hdl.handle.net/10722/91725
ISSN
2015 Impact Factor: 2.857
2015 SCImago Journal Rankings: 1.173
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorCheng, VCCen_HK
dc.contributor.authorTo, KKWen_HK
dc.contributor.authorLi, IWSen_HK
dc.contributor.authorTang, BSFen_HK
dc.contributor.authorChan, JFWen_HK
dc.contributor.authorKwan, Sen_HK
dc.contributor.authorMak, Ren_HK
dc.contributor.authorTai, Jen_HK
dc.contributor.authorChing, Pen_HK
dc.contributor.authorHo, PLen_HK
dc.contributor.authorSeto, WHen_HK
dc.date.accessioned2010-09-17T10:24:29Z-
dc.date.available2010-09-17T10:24:29Z-
dc.date.issued2009en_HK
dc.identifier.citationEuropean Journal Of Clinical Microbiology And Infectious Diseases, 2009, v. 28 n. 12, p. 1447-1456en_HK
dc.identifier.issn0934-9723en_HK
dc.identifier.urihttp://hdl.handle.net/10722/91725-
dc.description.abstractThe antimicrobial stewardship program (ASP) is a major strategy to combat antimicrobial resistance and to limit its expenditure. We have improved on our existing ASP to implement a sustainable and cost-effective two-stage immediate concurrent feedback (ICF) model, in which the antimicrobial prescription is audited by two part-time infection control nurses at the first stage, followed by "physician ICF" at the second stage. In January 2005, an ASP focused on broad-spectrum intravenous antibiotics was implemented. All in-patients, except from the intensive care, bone marrow transplantation, liver transplantation, pediatric, and private units, being treated with broad-spectrum intravenous antibiotics were included. The compliance to ICF and "physician ICF", antibiotics usage density measured by expenditure and defined daily doses (DDD) were recorded and analyzed before and after the ASP. The overall conformance rate to antibiotic prescription guidelines was 79.4%, while the conformance to ICF was 83.8%. Antibiotics consumption reduced from 73.06 (baseline, year 2004) to 64.01 (year 2007) per 1,000 patient bed-day-occupancy. Our model can be easily applied even in the clinical setting of limited resources. © 2009 Springer-Verlag.en_HK
dc.languageengen_HK
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/10096/index.htmen_HK
dc.relation.ispartofEuropean Journal of Clinical Microbiology and Infectious Diseasesen_HK
dc.subjectChemicals And Cas Registry Numbersen_HK
dc.subject.meshAnti-Bacterial Agents - therapeutic useen_HK
dc.subject.meshAttitude of Health Personnelen_HK
dc.subject.meshBacterial Infections - diagnosis - drug therapyen_HK
dc.subject.meshDrug Utilization - standardsen_HK
dc.subject.meshGuideline Adherence - statistics & numerical dataen_HK
dc.subject.meshHealth Services Researchen_HK
dc.subject.meshHospitalsen_HK
dc.subject.meshHumansen_HK
dc.subject.meshOrganizational Policyen_HK
dc.subject.meshPrescriptions - standardsen_HK
dc.titleAntimicrobial stewardship program directed at broad-spectrum intravenous antibiotics prescription in a tertiary hospitalen_HK
dc.typeArticleen_HK
dc.identifier.emailTo, KKW: kelvinto@hkucc.hku.hken_HK
dc.identifier.emailChan, JFW: jfwchan@hku.hken_HK
dc.identifier.emailHo, PL: plho@hkucc.hku.hken_HK
dc.identifier.authorityTo, KKW=rp01384en_HK
dc.identifier.authorityChan, JFW=rp01736en_HK
dc.identifier.authorityHo, PL=rp00406en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s10096-009-0803-8en_HK
dc.identifier.pmid19727869en_HK
dc.identifier.scopuseid_2-s2.0-71349084037en_HK
dc.identifier.hkuros261210-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-71349084037&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume28en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1447en_HK
dc.identifier.epage1456en_HK
dc.identifier.isiWOS:000271531200007-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridCheng, VCC=38662328400en_HK
dc.identifier.scopusauthoridTo, KKW=14323807300en_HK
dc.identifier.scopusauthoridLi, IWS=24464179500en_HK
dc.identifier.scopusauthoridTang, BSF=8908243000en_HK
dc.identifier.scopusauthoridChan, JFW=24278817900en_HK
dc.identifier.scopusauthoridKwan, S=35891301600en_HK
dc.identifier.scopusauthoridMak, R=35765617800en_HK
dc.identifier.scopusauthoridTai, J=7101993154en_HK
dc.identifier.scopusauthoridChing, P=7005847968en_HK
dc.identifier.scopusauthoridHo, PL=7402211363en_HK
dc.identifier.scopusauthoridSeto, WH=7005799377en_HK
dc.identifier.citeulike5736800-

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