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Conference Paper: The use of positron emission tomography in detecting hepatoblastoma recurrence - A cautionary tale

TitleThe use of positron emission tomography in detecting hepatoblastoma recurrence - A cautionary tale
Authors
KeywordsHepatoblastoma
positron emission tomography
tumor recurrence
Issue Date2004
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurg
Citation
37th Annual Meeting of the Pacific Association of Pediatric Surgeons, Seoul, Korea, 16-20 May 2004. In Journal Of Pediatric Surgery, 2004, v. 39 n. 12, p. 1779-1781 How to Cite?
AbstractPurpose The use of positron emission tomography (PET) with [18F] fluorodeoxyglucose (FDG) in the detection of recurrences has been well established in many tumor types. Here the authors present their experience using this modality in the evaluation of posttreatment hepatoblastoma patients. Methods The authors conducted a retrospective review on patients with hepatoblastoma diagnosed from 1996 to 2003. FDG-PET imaging was performed together with measurement of alpha-fetal protein (AFP) during posttreatment follow-up. Results Sixteen patients (8 boys and 8 girls) were identified in this series. The mean age was 23.5 months (range, 5 months to 4 years). Three posttreatment patients had PET results suggestive of tumor recurrence. One of these patients had normal AFP level and suspected recurrence in the caudate lobe. Radiologic-guided biopsy was performed 3 times, and there was no evidence of tumor. The other 2 patients underwent further liver resections because of mildly raised AFP levels. The histology of these showed regenerative liver tissue only with no hepatoblastoma recurrence. Conclusions Although PET has been gaining popularity as a tool in the detection of tumor recurrences worldwide, it has been shown in this series that PET may not be useful in hepatoblastoma patients, and caution must be taken in the interpretation of positive results. © 2004 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/83809
ISSN
2015 Impact Factor: 1.733
2015 SCImago Journal Rankings: 0.802
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, KKYen_HK
dc.contributor.authorLan, LCLen_HK
dc.contributor.authorLin, SCLen_HK
dc.contributor.authorTam, PKHen_HK
dc.date.accessioned2010-09-06T08:45:28Z-
dc.date.available2010-09-06T08:45:28Z-
dc.date.issued2004en_HK
dc.identifier.citation37th Annual Meeting of the Pacific Association of Pediatric Surgeons, Seoul, Korea, 16-20 May 2004. In Journal Of Pediatric Surgery, 2004, v. 39 n. 12, p. 1779-1781en_HK
dc.identifier.issn0022-3468en_HK
dc.identifier.urihttp://hdl.handle.net/10722/83809-
dc.description.abstractPurpose The use of positron emission tomography (PET) with [18F] fluorodeoxyglucose (FDG) in the detection of recurrences has been well established in many tumor types. Here the authors present their experience using this modality in the evaluation of posttreatment hepatoblastoma patients. Methods The authors conducted a retrospective review on patients with hepatoblastoma diagnosed from 1996 to 2003. FDG-PET imaging was performed together with measurement of alpha-fetal protein (AFP) during posttreatment follow-up. Results Sixteen patients (8 boys and 8 girls) were identified in this series. The mean age was 23.5 months (range, 5 months to 4 years). Three posttreatment patients had PET results suggestive of tumor recurrence. One of these patients had normal AFP level and suspected recurrence in the caudate lobe. Radiologic-guided biopsy was performed 3 times, and there was no evidence of tumor. The other 2 patients underwent further liver resections because of mildly raised AFP levels. The histology of these showed regenerative liver tissue only with no hepatoblastoma recurrence. Conclusions Although PET has been gaining popularity as a tool in the detection of tumor recurrences worldwide, it has been shown in this series that PET may not be useful in hepatoblastoma patients, and caution must be taken in the interpretation of positive results. © 2004 Elsevier Inc. All rights reserved.en_HK
dc.languageengen_HK
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurgen_HK
dc.relation.ispartofJournal of Pediatric Surgeryen_HK
dc.subjectHepatoblastomaen_HK
dc.subjectpositron emission tomographyen_HK
dc.subjecttumor recurrenceen_HK
dc.subject.meshChild, Preschool-
dc.subject.meshHepatoblastoma - radionuclide imaging-
dc.subject.meshLiver Neoplasms - radionuclide imaging-
dc.subject.meshNeoplasm Recurrence, Local - radionuclide imaging-
dc.subject.meshPositron-Emission Tomography-
dc.titleThe use of positron emission tomography in detecting hepatoblastoma recurrence - A cautionary taleen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0022-3468&volume=39&issue=12&spage=1779&epage=1781&date=2004&atitle=The+use+of+positron+emission+tomography+in+detecting+hepatoblastoma+recurrence+-+a+cautionary+taleen_HK
dc.identifier.emailWong, KKY: kkywong@hkucc.hku.hken_HK
dc.identifier.emailTam, PKH: paultam@hkucc.hku.hken_HK
dc.identifier.authorityWong, KKY=rp01392en_HK
dc.identifier.authorityTam, PKH=rp00060en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.jpedsurg.2004.08.033en_HK
dc.identifier.pmid15616927-
dc.identifier.scopuseid_2-s2.0-10944263806en_HK
dc.identifier.hkuros97083en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-10944263806&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume39en_HK
dc.identifier.issue12en_HK
dc.identifier.spage1779en_HK
dc.identifier.epage1781en_HK
dc.identifier.isiWOS:000226162400009-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWong, KKY=24438686400en_HK
dc.identifier.scopusauthoridLan, LCL=7005687228en_HK
dc.identifier.scopusauthoridLin, SCL=8213776500en_HK
dc.identifier.scopusauthoridTam, PKH=7202539421en_HK

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