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Article: Successful mismatched sibling cord blood transplant in Hb Bart's disease

TitleSuccessful mismatched sibling cord blood transplant in Hb Bart's disease
Authors
KeywordsCord blood transplantation
Hb Bart's disease
Hemoglobin F
HLA mismatched
Immune thrombocytopenia
Issue Date2001
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmt
Citation
Bone Marrow Transplantation, 2001, v. 28 n. 1, p. 105-107 How to Cite?
AbstractA 20-month-old girl with Hb Bart's disease, who had survived neonatal complications, underwent HLA-DR antigen mismatched sibling cord blood transplantation successfully. Immune thrombocytopenia, which occurred around 2.5 months after transplant, responded to intravenous γ-globulin. The fetal hemoglobin level rose to a peak of 52.3% on day +69 post transplant and declined gradually during the following year. Ten percent of hemoglobin Bart's was detected 2 months after transplant and this reflects the α-thalassemia trait of the donor.
Persistent Identifierhttp://hdl.handle.net/10722/77037
ISSN
2015 Impact Factor: 3.636
2015 SCImago Journal Rankings: 1.585
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorZhou, Xen_HK
dc.contributor.authorHa, SYen_HK
dc.contributor.authorChan, GCFen_HK
dc.contributor.authorLuk, CWen_HK
dc.contributor.authorChan, Ven_HK
dc.contributor.authorHawkins, Ben_HK
dc.contributor.authorLam, YHen_HK
dc.contributor.authorLiang, RHSen_HK
dc.contributor.authorLau, YLen_HK
dc.date.accessioned2010-09-06T07:27:35Z-
dc.date.available2010-09-06T07:27:35Z-
dc.date.issued2001en_HK
dc.identifier.citationBone Marrow Transplantation, 2001, v. 28 n. 1, p. 105-107en_HK
dc.identifier.issn0268-3369en_HK
dc.identifier.urihttp://hdl.handle.net/10722/77037-
dc.description.abstractA 20-month-old girl with Hb Bart's disease, who had survived neonatal complications, underwent HLA-DR antigen mismatched sibling cord blood transplantation successfully. Immune thrombocytopenia, which occurred around 2.5 months after transplant, responded to intravenous γ-globulin. The fetal hemoglobin level rose to a peak of 52.3% on day +69 post transplant and declined gradually during the following year. Ten percent of hemoglobin Bart's was detected 2 months after transplant and this reflects the α-thalassemia trait of the donor.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/bmten_HK
dc.relation.ispartofBone Marrow Transplantationen_HK
dc.subjectCord blood transplantationen_HK
dc.subjectHb Bart's diseaseen_HK
dc.subjectHemoglobin Fen_HK
dc.subjectHLA mismatcheden_HK
dc.subjectImmune thrombocytopeniaen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshFetal Blooden_HK
dc.subject.meshGraft Survivalen_HK
dc.subject.meshHLA-DR Antigensen_HK
dc.subject.meshHematopoietic Stem Cell Transplantation - adverse effects - methodsen_HK
dc.subject.meshHemoglobinopathies - blood - complications - therapyen_HK
dc.subject.meshHemoglobins, Abnormalen_HK
dc.subject.meshHistocompatibility - immunologyen_HK
dc.subject.meshHumansen_HK
dc.subject.meshInfanten_HK
dc.subject.meshNuclear Familyen_HK
dc.subject.meshPurpura, Thrombocytopenic, Idiopathic - drug therapy - etiologyen_HK
dc.subject.meshTransplantation, Homologous - adverse effects - immunology - methodsen_HK
dc.subject.meshalpha-Thalassemia - blood - complications - therapyen_HK
dc.titleSuccessful mismatched sibling cord blood transplant in Hb Bart's diseaseen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0268-3369&volume=28&spage=105&epage=107&date=2001&atitle=Successful+mismatched+sibling+cord+blood+transplant+in+Hb+Bart%27s+diseaseen_HK
dc.identifier.emailChan, GCF:gcfchan@hkucc.hku.hken_HK
dc.identifier.emailChan, V:vnychana@hkucc.hku.hken_HK
dc.identifier.emailLiang, RHS:rliang@hku.hken_HK
dc.identifier.emailLau, YL:lauylung@hkucc.hku.hken_HK
dc.identifier.authorityChan, GCF=rp00431en_HK
dc.identifier.authorityChan, V=rp00320en_HK
dc.identifier.authorityLiang, RHS=rp00345en_HK
dc.identifier.authorityLau, YL=rp00361en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/sj.bmt.1703104en_HK
dc.identifier.pmid11498754-
dc.identifier.scopuseid_2-s2.0-0034899954en_HK
dc.identifier.hkuros65285en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0034899954&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume28en_HK
dc.identifier.issue1en_HK
dc.identifier.spage105en_HK
dc.identifier.epage107en_HK
dc.identifier.isiWOS:000170111800017-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridZhou, X=22949652300en_HK
dc.identifier.scopusauthoridHa, SY=7202501115en_HK
dc.identifier.scopusauthoridChan, GCF=16160154400en_HK
dc.identifier.scopusauthoridLuk, CW=7005748744en_HK
dc.identifier.scopusauthoridChan, V=7202654865en_HK
dc.identifier.scopusauthoridHawkins, B=35944486200en_HK
dc.identifier.scopusauthoridLam, YH=7202563903en_HK
dc.identifier.scopusauthoridLiang, RHS=26643224900en_HK
dc.identifier.scopusauthoridLau, YL=7201403380en_HK

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